Bacitracin: Mechanism of Action, Pharmacokinetics, Uses, Side Effects by-The Medicine Library

Bacitracin:

Bacitracin ek polypeptide antibiotic hai jo aam taur par bacterial infection ke ilaj aur rok thaam ke liye istemaal hoti hai. Yah bacterium Bacillus subtilis se makhzu hai aur kayi dehaayiyon se tibi tor par istemaal ho raha hai. Is article mein, hum iski amal ka tareeqa kar, pharmacokinetics, spectrum, istemaal, dawaon ke taa'alluqat, zimni asarat ko talash karenge, aur bacitracin ke bare mein ek natija faraham karenge.

Amal ka tareeqa:

Bacitracin bacterial cell wall ki tarkeeb mein mudakhil ho kar apne antimicrobial asraat murattab karta hai. Yah khaas tor par ek lipd carrier molecule ke diphosphorylation ko rokta hai jise baktoprenol pyrophosphate kehte hain, jo ke khilayi ki jhilli mein peptidoglycan peyshiyon ki naqal o hamal ke liye zaroori hai. Is amal ko rok kar, bacitracin bacterial cell wall ki assembly mein khilaal dalta hai, jis se cell ki maut hoti hai.

Dawasazi:

Bacitracin bunyadi taur par ek topical formulation ke tor par dastiyab hai aur jab jild par lagaya jata hai toh yah nazami tor par achhi tarah jazb nahi hota hai. Iski zubani hayatiyati dastiyabi mehdood hai aur nazami istemaal ke liye iski sifarish nahi ki jati hai. Jab upri tor par lagaya jata hai, bacitracin kam se kam bareqarar jild ke zariye jazb hota hai, lekin agar jild ko nuqsaan pahuncha ho ya agent ko bade sathwi alaqon ya zyada irtiqaz mein lagaya jaye toh jazb barh sakta hai.

Spectrum:

Bacitracin mein bunyadi taur par gram-positive bacteria ke khilaf sargarmi ka ek tang daireh hai, beshumar Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, aur Clostridium perfringens ke kuch tanao. Yah gram-negative bacteria ke khilaf mufeed nahi hai. Bacitracin aam taur par surface-level jild ke infections ko rokne aur ilaj karne ke liye istemaal hota hai, jaise impetigo, mamooli kuto'tiyan, jalan, aur ragnaa.

Istemaal karta hai:

Bacitracin bunyadi taur par jild ke infection ke ilaj aur rok thaam ke liye istemaal hota hai. Yah aksar over-the-counter antibiotic creams aur kreamon mein shamil hota hai. Bacitracin ko jild ke mamooli infection ke bunyadi ilaj ke taur par ya zyada sangeen surton mein doosre systemic antibiotic ke saath milhak ke taur par istemaal kiya ja sakta hai. Yah note karna zaroori hai ke bacitracin nazami infection ke khilaf mufeed nahi hai aur ise aise maqas.

Bura asarat:

Bacitracin ko aam tor par mehfuz aur achi tarah bardasht kiya jata hai jab upri tor par istemaal kiya jata hai. Tahaam, kuch afraad darkhwast ki jagah par makhmali allergik rad-e-amal ka tajurba kar sakte hain, jaise lalima, kharish, ya jalan. Agar ye alamat zaahir hoti hain toh, bacitracin ko band karne aur sehat ki dekhbhaal karne wale paishwar se mashwara karne ki sifarish ki jati hai. Bacitracin ka systematic jazb kam se kam hota hai jab topical tor par istemaal kiya jata hai, jis se systematic zimni asarat ka khatra kam hota hai.

Natija:

Bacitracin ek topical antibiotic hai jo aam tor par surface-level jild ke infections ke ilaj aur rok thaam ke liye istemaal hoti hai. Iska amal ka tareeqa kar, bacterial cell wall ki tashkeel ko rokta hai, ise gram-positive bacteria ke khilaf mufeed banata hai. Bacitracin aam tor par achi tarah bardasht kiya jata hai, aur nazamati zimni asarat ka khatra kam hota hai. Tahaam, ye zaroori hai ke bacitracin ko hidayat ke mutabiq istemaal kiya jaye na ke nazami infection ke liye. Mijmua'i tor par, bacitracin dermatological practice mein ek qabil-e-qadar kirdar ada karta hai aur surface-level bacterial infections ke intizam mein taawun karta hai.