Lidocaine hydrochloride | Drugs | BNF | NICE..by-The Medicine Library

Lidocaine:

Taruf:

Lidocaine ya lignocaine, aik maqami anasthetic dawa hai jo tibi tareeqa kar ya surgery ke duran dard ya takleef ko kam karne ke liye jism ke aik makhsoos hissay mein tishu ko be hiss karne ke liye istemaal hoti hai. Lidocaine aasabi tarikukon ko rok kar kaam karta hai jo dimagh ko dard ke signal bhejte hain, is tarah dard ko kam ya khatam karte hain.

Amal ka tareeka:

Lidocaine aik aesa dawa hai jo aasabi jhilli mein sodium channels ko rok kar kaam karta hai. Is tarah aasabi khaliyon mein sodium aayon ki aamad ko rokta hai. Is se aasabi khaliyon ke depolarization mein kami hoti hai, jis ke natijay mein action potential ka toal-o-arz-o-daurania kam hojata hai. Is tarah aasabi tahreekon ki transmission ko rokta hai. Lidocaine mein vasodilatory khosusiyaat bhi hain, jo usay mutasirah ilaqe mein khoon ke behaao ko barhane, shifa yabi ko farogh dene aur sozish ko kam karne ki ejazat deti hain. Dawasazi:  Lidocaine jild aur chupchapa jhilliyon ke zariye tezi se jazb hota hai aur jigar ke zariye baray paimane par metabolism hota hai. Is ki nisf zindagi taqreeban 1.5 se 2 ghantay hoti hai, aur is ke asrat aam tor par taqreeban 1-2 ghantay tak rehtay hain. Manshiyat peshab aur pakhanay mein kharij hoti hai, aur is ki metabolites bunyadi tor par peshab mein kharij hoti hain.

Spectrum:

Lidocaine aam tor par maqami behoshi ki dawa ke tor par istemal kiya jata hai, lekin yeh dil ki taal ki kharabiyon jaise ventricular arrhythmias ke ilaj ke liye ek anti-arrhythmic dawa ke tor par bhi istemal kiya ja sakta hai. Mazeed baran, Lidocaine ko postherpetic neuralgia ke ilaj mein istemal kiya jata hai, aasabi dard ki aik qisam jo shingles ki aik qisat ke baad hoti hai.

Istemal karna ka tareeqa:

Lidocaine mukhtalif qisam ke tibi tariqay kar aur surgeryon mein dard ya takleef ko kam karne ke liye istemal kiya jata hai, jaise danton ke tariqay kar, mamuli jarahi ke tariqay kar, aur amraz-e-niswan ke tariqay kar. Yeh jild ki baaz halat ke ilaj mein bhi istemal hota hai, jaise ke khushki aur chhapaki. Lidocaine ko aasabi block ke tor par bhi istemal kiya ja sakta hai, jis mein iss aasab ke zariye faraham kiya gaya ilaqe ko be hiss karne ke liye dawa ko brah-e-raast aasab mein injection lagana shamil hai.

Manshiyat k sath ta'alluq:

Lidocaine kai dawayon ke saath ta'alluq kar sakta hai, beshumar beta blockers, jo zehreela honay ka khatra barha saktay hain, aur cimetidine, jo lidocaine ke metabolism ko kam kar sakta hai, jis se khoon ke dhaaray mein manshiyat ki satah barh jati hai. Lidocaine digar maqami anesthetic, antiarrhythmic adwiyat, aur baaz anti-biotic ke saath bhi ta'alluq kar sakti hai.

Muzir Asraat:

Lidocaine ke sab se aam zimni asraat halkay hotay hain aur in mein injection ki jagah par aarzi jalan ya dankanay ka ehsas shamil hota hai. Zyada sangin zimni asraat ho saktay hain, jaisay allergy ka rad-e-amal, jo soojan, chhante aur saans lenay mein mushkil ka sabab ban sakta hai. Lidocaine aasabi zimni asraat ka bhi sabab ban sakta hai, jaisay dore, uljhan aur chakkar aana. Mazeed baran, Lidocaine cardiac zimni asraat ka sabab ban sakta hai, jaisay bradycardia, hypertension, aur cardiac girt.

Natija:

Lidocaine aik ahem dawa hai jo tibi tareeqa kar aur surgery kay doran dard aur takleef kay intizam mein istemaal hoti hai. Iss kay amal kay tareeqa mein aasabi jhilli mein sodium channels ko rokna, aasabi tahrakukon ki tarseel ko kam karna shamil hai. Lidocaine ki nisf zindagi mukhtasar hai, aur iss kay asraat aam tour par taqreeban 1-2 ghantay tak rehtay hain. Lidocaine aam tour par achi tarah se bardasht ki jati hai, lekin yeh sangin zimni asraat ka sabab ban sakta hai, khas tor par agar ghalat tareeqay se ya zyada miqdaar mein istemaal kiya jaye. Lidocaine ka istemaal sirf aik mustanad tibi pesha war ki rehnumai mein karna zaroori hai jo iss kay istemaal mein tajriba kar ho.