CALPOL: Mechanism of Action, Pharmacokinetics, Uses, Side Effects by-The Medicine Library

Calpol:

Taruf:

Calpol ek maqbool over the counter (OTC) dawaiyon ke liye ek wasee pemanay par tasleem shuda brand ka naam hai jis mein fa'al juz paracetamol (acetaminophen) hota hai. Yah aam tour par bachon aur badoon dono mein dard ko door karne aur bukhar ko kam karne ke liye istemaal hota hai. Is jamey jaizay mein, hum amal ke tareeqay kar, pharmaco-kinetics, spectrum, istemaal, manshiyat ke ta'amulat, zameeni asrat, aur Calpol ki afadiyat aur hifazat ke bare mein ek natija ikhteyar karenge.

Amal ka tareeqa kar:

Paracetamol, Calpol mein fa'al juz, ek analgesic (dard ko kam karne wala) aur antipyretic (bukhar kam karne wala) ke tor par darja bandi kiya jata hai. Is ke amal ka sahi tareeqa kar puri tarah se samjha jata hai, lekin khayal kya jata hai ke yeh prostaglandins ki paidawar ko rok kar kaam karta hai, jo dard aur bukhar mein milawat chemi messenger hain. Markazi asabi nizam mein prostaglandins ki tarkib ko kam karke, paracetamol dard ko kam karne aur jism ke darja hararat ko kam karne mein madad karta hai.

Dawasazi:

Zabani istemaal ke baad, paracetamol made ki naali se tezi se jazb ho jata hai aur 30 se 60 minute ke andar plasma ki buland tareen satah tak pohanch jata hai. Yah pure jism mein bade pemanay par taqseem kiya jata hai, bishmol markazi asabi nizam, plasma protein ke sath kam se kam pabandi ke sath. Paracetamol bunyadi tor par jigar mein glucuronidation aur sulfation ke zariye metabolize hota hai, aur ek chhota sa hissa cytochrome P450 enzyme system ke zariye oxidation se guzarta hai. Metabolites bunyadi tor par peshab mein kharij hote hain. Paracetamol ki nisf zindagi balghon mein taqriban 2 se 3 ghante hoti hai.

Spectrum:

Calpol, paracetamol par mushtamil, halkay se itidal pasand dard, jaise sir dard, daant ka dard, pathon mein dard, aur mamooli zakhmon se mansalik dard ko door karne mein muassir hai. Yah mukhtalif halaat ki wajah se hone wale bukhar ko kam karne ke liye bhi istemal hota hai, bishmol aam nazla, flu, aur vaccination. Calpol mukhtalif umar ke afraad ke liye muzoon hai, bishmol shirakhuwar, bachay aur baligh.

Tibbi Istemal:

Calpol aam tor par sir dard, danton ke dard, mahvari ke dard, aur pathon ki chotoun se wabasta dard ko kam karne ke liye istemal kiya jata hai.

Bukhar mein kami: 

Calpol ek bharosa mand jaraseem kash dawa hai jo mukhtalif bemariyon ki wajah se hone wale bukhar ko kam karne ke liye istemal hoti hai, jaise ki viral infection aur vaccination ke baad hone wale rad-e-amal.

Bachon ka istemal:

 Calpol ki afadiyat, hifazati profile, aur bachon ke liye muzoon formulations mein dastiyab honay ki wajah se dard se nijat aur bukhar mein kami ke liye bachon ko baray paimanay par diya jata hai.

Manshiyat ka taamul:

Agarche paracetamol ko aam tor par mehfooz samjha jata hai, lekin manshiyat ke mumkin taamul se aaghah hona zaroori hai. Paracetamol baaz dawao ke saath taamul kar sakta hai, jaise warfarin, khoon behne ka khatra barhata hai. Mutabiqat aur hifazat ko yaqeeni banane ke liye Calpol ko doosri adwiyat ke saath milanay se pehle sehat ki dekh bhaal karne wale peshawar ya pharmacist se mashwara karna bohat zaroori hai.

Muzir asraat:

Calpol ko aam tor par achhi tarah se bardasht kia jata hai jab hidayat ke mutabiq istemal kia jaye. Taham, kisi bhi dawa ki tarah, is ke muzir asraat ho sakte hain. Paracetamol ke saath mansalik sab se zyada aam manfi waqeat halkay aur kabhi kabhar hote hain, bishmul matli, peet ki kharabi, aur jild par kharish. Sangin zimni asraat nayab hain lekin ho sakte hain, jaise ke shadeed allergik rad-e-amal ya zyada ya taweel istemal ki surat mein jigar ka zehreela hona. Tajweez karda khoraak par amal karna aur koi ghair mamooli alamat zahir hone par tibbi imdad hasil karna bohat zaroori hai.

Natija:

Calpol, paracetamol par mushtamil, ek wasee paimanay par istemal hone wali OTC dawa hai jo dard ko kam karne aur bukhar ko kam karne mein apni taseer ke liye mashhoor hai. Yeh prostaglandins ki paidawar ko rok kar inflammation aur anti-pyretic ke tor par kaam karta hai. Paracetamol taizi se jazb hota hai, wasee paimanay par taqseem hota hai aur bunyadi tor par jigar mein metabolize hota hai.